A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NF-kB
Type TF
Species Homo sapiens
Tissue NA
Experiment Method other
Up/Down Up
Pro/Anti Pro
Funtion Description These findings indicate that impaired function with aging in healthy adults is associated with the development of a proinflammatory phenotype in the vascular endothelium that could be caused in part by reduced IkB-mediated activation of NFkB.
Regulation Gene NA
Year 2008
Pubmed ID 18782346
Title Aging is Associated with Greater Nuclear NFkB, Reduced IkBa and Increased Expression of Proinflammatory Cytokines in Vascular Endothelial Cells of Healthy Humans
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA