A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NF-kB
Type TF
Species Rat Rattus
Tissue liver and kidney tissues
Experiment Method RNAi,qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description Damage to liver and kidney function was significantly alleviated in the EGCG group. In addition, EGCG decreased the mRNA and protein expressions of transcription factor NF-kB and increased the upstream protein expressions of silent mating type information
Regulation Gene NA
Year 2013
Pubmed ID 23834676
Title The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age-associated inflammation and oxidative stress in healthy rats
Drug NA
Disease age-related inflammation
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA