A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NF-kB
Type TF
Species Mus musculus
Tissue liver tissues
Experiment Method Western Blotting,qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description To determine whether NF-kB drives aging in response to the accumulation of spontaneous, endogenous DNA damage, we measured the activation of NF-kB in WT and progeroid model mice. As both WT and progeroid mice aged, NF-kB was activated stochastically in a
Regulation Gene NA
Year 2012
Pubmed ID 22706308
Title NF-kB inhibition delays DNA damage-induced senescence and aging in mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA