Details
| Name | NF-kB |
| Type | TF |
| Species | Homo sapiens |
| Tissue | Human diploid IMR-90 fibroblasts |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Through a proteomics analysis of senescent chromatin, we identified the nuclear factor-kB (NF-kB) subunit p65 as a major transcription factor that accumulates on chromatin of senescent cells. We found that NF-kB acts as a master regulator of the SASP, inf |
| Regulation Gene | NA |
| Year | 2011 |
| Pubmed ID | 21979375 |
| Title | Control of the senescence-associated secretory phenotype by NF-kB promotes senescence and enhances chemosensitivity |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |