A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NF-kB
Type TF
Species Rat Rattus
Tissue Rat endothelial cell lines YPEN-1
Experiment Method Western Blotting
Up/Down Down
Pro/Anti Pro
Funtion Description The results of the analysis showed that Ang II and AT1 expression increased during aging and that these increases were blunted by treatment with genistein. Furthermore, we investigated the inhibitory effects of genistein on the Ang II-induced redox imbala
Regulation Gene NA
Year 2011
Pubmed ID 21713398
Title Mechanism of attenuation of pro-inflammatory Ang II-induced NF-kB activation by genistein in the kidneys of male rats during aging
Drug NA
Disease NA
Environment Factors Ang II
Circulating NA
Variant NA
High-throughput NA