A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Nrf2
Type TF
Species Homo sapiens
Tissue human diploid fibroblasts
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description Using different techniques, we show for the first time an accumulation of copper in cells during replicative senescence. This accumulation seems to be co-localized with lipofuscin. Second, we observed that an incubation of cells with copper sulfate induce
Regulation Gene NA
Year 2013
Pubmed ID 23576095
Title Role of p38MAPK and oxidative stress in copper-induced senescence
Drug NA
Disease NA
Environment Factors copper
Circulating NA
Variant NA
High-throughput NA