Details
| Name | Nrf2 |
| Type | TF |
| Species | Drosophila melanogaster |
| Tissue | Drosophila samples |
| Experiment Method | Western Blotting,ChIP |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Here, we show that the expression of protective Nrf2/CncC target genes in unstressed conditions does not generally decrease in older flies. However, aging flies progressively lose the ability to activate Nrf2 targets in response to acute stress exposure. |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23521918 |
| Title | Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |