A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name E2F/DP
Type gene
Species Homo sapiens
Tissue NA
Experiment Method RT-PCR
Up/Down Down
Pro/Anti Pro
Funtion Description E2F/DP activity is indeed essential for cell proliferation and its reduction immediately provokes a senescence-like cell cycle arrest.
Regulation Gene NA
Year 2005
Pubmed ID 15716376
Title Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA