A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Nrf2
Type TF
Species Mus musculus
Tissue hair cells
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description In this study, we examined the roles of Nrf2 in age-related hearing loss and gentamicin ototoxicity by measuring auditory brainstem response thresholds in Nrf2-knockout mice. Although Nrf2-knockout mice maintained normal auditory thresholds at 3 months of
Regulation Gene antioxidant enzymes and detoxifying proteins
Year 2011
Pubmed ID 22020098
Title Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA