A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Nrf2
Type TF
Species Macaca mulatta
Tissue vascular smooth muscle cells
Experiment Method Western Blotting,qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description In contrast, in cultured vascular smooth muscle cells cells derived from aged macaques, H(2)O(2)- and high glucose-induced Nrf2 activity and Nrf2-driven gene expression are blunted. High glucose-induced H(2)O(2) production was significantly increased in a
Regulation Gene NA
Year 2011
Pubmed ID 21622983
Title Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA