Details
| Name | Nrf2 |
| Type | TF |
| Species | Mus musculus |
| Tissue | bone marrow;spleen;peritoneal cavity |
| Experiment Method | RT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Kinases Mst1 and Mst2 (Mst1/2) sense ROS and maintain cellular redox balance by modulating the stability of antioxidant transcription factor Nrf2. Site-specific ROS release recruits Mst1/2 from the cytosol to the phagosomal or mitochondrial membrane, with |
| Regulation Gene | NA |
| Year | 2019 |
| Pubmed ID | 30765703 |
| Title | Macrophage achieves self-protection against oxidative stress-induced through the Mst-Nrf2 axis |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |