Details
| Name | Nrf2 |
| Type | TF |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | qPCR,Western blot |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | To determine whether age-related activation of ERK1/2-AP-1 signaling is responsible for the up-regulation of GCLC, the MEK inhibitors, PD98059 and U0126, were used to block ERK1/2 in VSMC from old rats. An increase in GCLC with inhibitors was observed, di |
| Regulation Gene | NA |
| Year | 2006 |
| Pubmed ID | 16155909 |
| Title | Age affects ERK1/2 and NRF2 signaling in the regulation of GCLC expression. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |