A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Nrf2
Type TF
Species Mus musculus
Tissue C57bl/6 mice, naked mole-rats, white-footed mice, deer mice, guinea pigs, gerbils, and hamsters
Experiment Method Immunoblotting;Real-Time PCR;Immunoprecipitation
Up/Down NA
Pro/Anti Anti
Funtion Description We found that longer-lived rodent species had markedly higher levels of signaling activity of the multifunctional regulator nuclear factor erythroid 2-related factor (Nrf2) and that this increase in cytoprotective signaling appeared to be due to species d
Regulation Gene NA
Year 2015
Pubmed ID 25775529
Title Regulation of Nrf2 signaling and longevity in naturally long-lived rodents.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA