| Name |
PPARr
|
| Type |
TF
|
| Species |
Homo sapiens
|
| Tissue |
lung fibroblast tissue
|
| Experiment Method |
Luciferase reporter assay,ChIP,qPCR,western blot
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
In addition, PPARr promotes cellular senescence by inducing p16INK4a (CDKN2A), which is an important cell-cycle inhibitor
|
| Regulation Gene |
SIRT1
|
| Year |
2010
|
| Pubmed ID |
20660480
|
| Title |
SIRT1 is regulated by a PPARr-SIRT2 negative feedback loop associated with senescence
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|