Details
| Name | REST |
| Type | TF |
| Species | Homo sapiens |
| Tissue | human MIAMI cells |
| Experiment Method | RT-qPCR;Western blot;Immunoprecipitation;immunofluorescence |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | We demonstrate that low oxygen stimulates a complex signaling network involving PI3K/Akt, Notch, and canonical Wnt pathways, which mediate the observed increase in nuclear Oct4a and REST, with simultaneous decrease in p53, AIF, and Bak. Collectively, thes |
| Regulation Gene | NA |
| Year | 2016 |
| Pubmed ID | 27059084 |
| Title | Low Oxygen Modulates Multiple Signaling Pathways, Increasing Self-Renewal, While Decreasing Differentiation, Senescence, and Apoptosis in Stromal MIAMI Cells. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |