A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name retinol
Type TF
Species Homo sapiens
Tissue sun-protected buttock skin of human volunteers
Experiment Method Immunohistology;RNA isolation and Northern blot analysis;RT-PCR;Western blot
Up/Down NA
Pro/Anti Anti
Funtion Description Topical ROL shows remarkable anti-ageing effects through three major types of skin cells: epidermal keratinocytes, dermal endothelial cells and fibroblasts. Topical ROL significantly increased epidermal thickness by stimulating keratinocytes proliferation
Regulation Gene NA
Year 2017
Pubmed ID 27261203
Title Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA