Details
| Name | RUNX2 |
| Type | TF |
| Species | Mus musculus |
| Tissue | RNeasy Lipid Tissue |
| Experiment Method | ChIP assay,RT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Maf is one of the potential candidate genes underlying an age-related decrease in osteoblastogenesis.Over expression of Maf resulted in effective restoration of both an accelerated aging phenotype in Maf+/- mice and age-related changes in WT mice. |
| Regulation Gene | Maf |
| Year | 2010 |
| Pubmed ID | 20877012 |
| Title | Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. |
| Drug | antidiabetic drugs |
| Disease | osteoporosis |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | somatic mutation |
| High-throughput | NA |