| Name |
SAFA
|
| Type |
TF
|
| Species |
Homo sapiens
|
| Tissue |
Primary human diploid fibroblast strains, BJ (neonatal foreskin) and WI38 (fetal lung)
|
| Experiment Method |
Co-immunoprecipitation and western blotting;Chromatin immunoprecipitation;Immunofluorescence;qRT-PCR;Native RNA immunoprecipitation;EMSA
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
Here we demonstrate that scaffold-attachment-factor A (SAFA) and the long noncoding RNA PANDA differentially interact with polycomb repressive complexes (PRC1 and PRC2) and the transcription factor NF-YA to either promote or suppress senescence. In prolif
|
| Regulation Gene |
NA
|
| Year |
2014
|
| Pubmed ID |
25406515
|
| Title |
Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|