A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SKN-1
Type TF
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method qPCR,RNAi
Up/Down NA
Pro/Anti Anti
Funtion Description SKN-1 contributes to the increased stress tolerance and longevity resulting from reduced IIS, and delays aging when expressed transgenically. Furthermore, SKN-1 that is constitutively active increases lifespan independently of DAF-16. Our findings indicat
Regulation Gene gst-7
Year 2008
Pubmed ID 18358814
Title Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA