A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SKN-1
Type TF
Species Caenorhabditis elegans
Tissue C. elegansstrains
Experiment Method RNA interference;RNA isolation and quantitative PCR
Up/Down NA
Pro/Anti Anti
Funtion Description we show that inhibition of cell cycle genes leads to tolerance towards environmental stress and longevity. The reproductive system is known as a key regulator of longevity in C. elegans. We uncovered the gonad as the central organ mediating the effects of
Regulation Gene NA
Year 2016
Pubmed ID 27668945
Title Cell cycle controls stress response and longevity inC. elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA