| Name |
SOX2
|
| Type |
TF
|
| Species |
Homo sapiens
|
| Tissue |
HEK293T, HCT116, CCD-18Co, HT29, and WiDr cells
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
Here, we found that Sox2, a key transcription factor in the regulation of the stemness of embryonic stem cells and induced-pluripotent stem cells, strongly induced autophagic phenomena, including intracellular vacuole formation and lysosomal activation in
|
| Regulation Gene |
NA
|
| Year |
2013
|
| Pubmed ID |
23451179
|
| Title |
Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells
|
| Drug |
NA
|
| Disease |
colon cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|