Details
| Name | SP1 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | NIH-H460,MCF7 |
| Experiment Method | qPCR,Western blot |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | In the cells treated with other DNA damaging chemicals such as actinomycin D and H(2)O(2), the Sp1 level decreased progressively as well. Inhibition of ATM/ATR kinases prevented this downregulation, suggesting that DNA damage signaling is involved in the |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17161377 |
| Title | Downregulation of transcription factor, Sp1, during cellular senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |