A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SPI/PU.1
Type TF
Species Mus musculus
Tissue muscle tissues
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description We show that shifts in the abundance of S100a8 and S100a9 mRNA are a robust feature of aging in mammalian tissues, involving a range of cell types including the central nervous system. To identify transcription factors that control S100a9 expression, we p
Regulation Gene S100a9
Year 2013
Pubmed ID 23386971
Title Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation
Drug NA
Disease chronic inflammation
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA