A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Spi1/PU.1
Type TF
Species Mus musculus
Tissue blood
Experiment Method PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description The Spi1/PU.1 transcription factor is a key regulator of many steps of hematopoiesis, and limits self-renewal of hematopoietic stem cells.
Regulation Gene NA
Year 2018
Pubmed ID 28912174
Title Senescence is a Spi1-induced anti-proliferative mechanism in primary hematopoietic cells.
Drug NA
Disease acute myeloid leukemia
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA