Details
| Name | E47 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | ATCC |
| Experiment Method | RT-PCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | E47 uniformly inhibited PDA cell-cycle progression by decreasing expression of MYC, increasing the level of CDKN1B/p27KIP1, and restoring RB tumor-suppressor function. The molecular mechanisms by which E47 elicited these changes included altering both RNA |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 30003124 |
| Title | E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53. |
| Drug | NA |
| Disease | RB |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | GSE100327 |