Details
| Name | SREBP |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | RNAi;qRT-PCR |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | Here, we show that sterol regulatory element-binding protein (SREBP) and mediator-15 (MDT-15) prevent the life-shortening effects of a glucose-rich diet by regulating fat-converting processes in Caenorhabditis elegans.Up-regulation of the SREBP/MDT-15 tra |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 26637528 |
| Title | SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |