A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name STAT1
Type TF
Species Homo sapiens
Tissue human mesangial cells
Experiment Method RNAi,Western Blotting,qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description In our study, induction of Angiotensin II (Ang II) and H(2)O(2) accelerated premature senescence of HMCs as confirmed by increased senescence-associated -B-galactosidase (SA-B-gal) positive staining cells and G0/G1 cell cycle arrest. The STAT1 and STAT3 a
Regulation Gene NA
Year 2012
Pubmed ID 22193460
Title STAT1 mediates cellular senescence induced by angiotensin II and HO in human glomerular mesangial cells
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA