Details
| Name | TBX2 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | primary human lung fibroblasts |
| Experiment Method | RNAi,ChIP,qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | We identify TBX2, a T-box transcription factor frequently overexpressed in cancer, as a novel and direct PML-repressible E2F-target gene in senescence but not quiescence. Recruitment of PML to the TBX2 promoter is dependent on a functional p130/E2F4 repre |
| Regulation Gene | E2F |
| Year | 2012 |
| Pubmed ID | 22002537 |
| Title | Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |