A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TFAM
Type TF
Species Mus musculus
Tissue muscle tissues
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description The purpose of this study was to investigate the effect of mtDNA mutations on mitochondrial quality control processes in skeletal muscle from animals (young; 3-6 months and older; 8-15 months) expressing a proofreading-deficient version of mtDNA polymeras
Regulation Gene NA
Year 2013
Pubmed ID 23935986
Title Dysregulation of mitochondrial quality control processes contribute to sarcopenia in a mouse model of premature aging
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA