A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TFAM
Type TF
Species Rat Rattus
Tissue bilateral cochleae
Experiment Method Western Blotting,qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description In the present study, a rat mimetic aging model induced by D-Gal was used to explore the origin of deletion mutations and how mtDNA repair systems modulate this process in the inner ear during aging. We found that the mitochondrial common deletion was gre
Regulation Gene NA
Year 2011
Pubmed ID 21575134
Title Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging.
Drug NA
Disease presbycusis
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA