Details
| Name | TFAM |
| Type | TF |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Together, an overexpression of TFAM is therefore considered to ameliorate age-dependent impairment of the brain functions through the prevention of oxidative stress and mitochondrial dysfunctions in microglia. |
| Regulation Gene | mtDNA |
| Year | 2008 |
| Pubmed ID | 18716221 |
| Title | Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | Oxidation |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |