Details
| Name | TFEB |
| Type | TF |
| Species | Rat Rattus |
| Tissue | NP cells |
| Experiment Method | qPCR |
| Up/Down | Up |
| Pro/Anti | pro |
| Funtion Description | The nuclear localization of TFEB declined in degenerated rat NP tissue as well as in TBHP treated NP cells. Applying lentivirus to transfect NP cells, TFEB overexpression restored the TBHP-induced autophagic flux blockage and protected NP cells against ap |
| Regulation Gene | NA |
| Year | 2019 |
| Pubmed ID | 30414849 |
| Title | TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |