A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name UNC-104
Type TF
Species Caenorhabditis elegans
Tissue C. elegans strain
Experiment Method RT-PCR
Up/Down Up
Pro/Anti Anti
Funtion Description we uncover a surprising role of the anterograde molecular motor UNC-104/KIF1A as a key regulator of neural circuit deterioration in aging C. elegans. Through analyses of synapse protein localization, synaptic transmission, and animal behaviors, we find th
Regulation Gene NA
Year 2016
Pubmed ID 26877087
Title The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA