A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name UNC-120/SRF
Type TF
Species Caenorhabditis elegans
Tissue muscle
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description The role of UNC-120/SRF in the control of muscle aging can be dissociated from its broader effect on lifespan. In daf-2/insulin/ IGF1 receptor mutants, which exhibit a delayed appearance of muscle aging biomarkers and are long-lived, disruption of unc-120
Regulation Gene NA
Year 2018
Pubmed ID 29314608
Title UNC-120/SRF independently controls muscle aging and lifespan in Caenorhabditiselegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA