A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name VEG
Type TF
Species Mus musculus
Tissue EGM-2 medium (Clonetics), Human WI-38 and IMR90 (fetal lung), HCA2 and BJ (foreskin) fibroblasts
Experiment Method qPCR,Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description This result suggests the rise in VEGF expression at senescence is not a hypoxic response. Our findings may in part explain why senescent cells stimulate tumorigenesis in vivo and support the idea that senescent cells may facilitate age-associated cancer d
Regulation Gene NA
Year 2006
Pubmed ID 16880208
Title Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA