Details
| Name | WT1 |
| Type | TF |
| Species | Mus musculus |
| Tissue | mouse lung tumor cell lines (LKR10 and LKR13) |
| Experiment Method | qPCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Using a combination of functional genomics and mouse genetics, we identified a role for the transcription factor Wilms tumor 1 (WT1) as a critical regulator of senescence and proliferation downstream of oncogenic KRAS signaling. Deletion or suppression of |
| Regulation Gene | NA |
| Year | 2010 |
| Pubmed ID | 20972333 |
| Title | Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models |
| Drug | NA |
| Disease | lung cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |