A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Klf4
Type gene
Species Mice
Tissue NA
Experiment Method NA
Up/Down Down
Pro/Anti Pro
Funtion Description Our results indicate that loss of rhythmic Klf4 expression in aged macrophages is associated with disruption of circadian innate immune homeostasis, a mechanism that may underlie age-associated loss of protective immune responses.
Regulation Gene NA
Year 2022
Pubmed ID 34949832
Title Aging disrupts circadian gene regulation and function in macrophages
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA