A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ABT-263
Type gene
Species Mouse
Tissue cecal slurry
Experiment Method RT-PCR,Western Blot
Up/Down NA
Pro/Anti Pro
Funtion Description RT-PCR and Western Blot were used to detect autophagy related gene and protein changes in sepsis. EGFP-expressing E. coli was used as a marker to evaluate the phagocytic ability of macrophages.
Regulation Gene NA
Year 2021
Pubmed ID 33794800
Title ABT-263 enhanced bacterial phagocytosis of macrophages in aged mouse through Beclin-1-dependent autophagy
Drug NA
Disease Sepsis
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA