A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name V338Y
Type methylation
Species Mouse
Tissue Brain
Experiment Method RNA-Seq
Up/Down NA
Pro/Anti Pro
Funtion Description Using a combination of unbiased RNA-Seq with untargeted metabolomics, we here demonstrate a concerted response, which alleviates the impaired functionality of OXPHOS complexes in Mrps5 mutant mice.
Regulation Gene NA
Year 2021
Pubmed ID 33803109
Title Mitochondrial Mistranslation in Brain Provokes a Metabolic Response Which Mitigates the Age-Associated Decline in Mitochondrial Gene Expression
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA