A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FBXO33
Type gene
Species Homo sapiens
Tissue NA
Experiment Method GWAS
Up/Down Up
Pro/Anti Pro
Funtion Description This analysis identified 37 loci associated with blood lipids but only one locus, FBXO33, was not reported in previous top GWAS. We, however, found strong effect of antagonistic heterogeneity that leaded to profound (quantitative and qualitative) changes in the associations with blood lipids in most, 25 of 37 or 68%, loci.
Regulation Gene FBXO33
Year 2020
Pubmed ID 31566214
Title Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null