A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BDNF
Type gene
Species Homo sapiens
Tissue brain
Experiment Method linear mixed models
Up/Down Up
Pro/Anti Pro
Funtion Description Addition of interaction effects showed significant differences in rate of decline between activity levels, particularly among males (p = .006). A three-way interaction with sex, NGFR SNP rs2072446, and physical activity suggested that the C/C allele was associated with better cognitive performance among males engaging in light activity only (p = .004).
Regulation Gene BDNF
Year 2020
Pubmed ID 31504225
Title Interaction Between Physical Activity and Genes Related to Neurotrophin Signaling in Late-Life Cognitive Performance: The Cache County Study.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null