A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ELOVL4
Type gene
Species Homo sapiens
Tissue glioblastoma cells line
Experiment Method PCR,other
Up/Down Down
Pro/Anti Pro
Funtion Description A highly reduced activity of the ELOVL4 promoter was registered due to combination of two variants. Decrease of ELOVL4 enzymatic activity could lead to a deficiency of VLC-PUFA, essential components for rods function and longevity, which are among the par
Regulation Gene NA
Year 2018
Pubmed ID 29417145
Title Stargardt Phenotype Associated With Two ELOVL4 Promoter Variants and ELOVL4 Downregulation: New Possible Perspective to Etiopathogenesis
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA