A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SORBS3
Type gene
Species Mice
Tissue NA
Experiment Method RT-qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Here, we describe that autophagosome biogenesis declines with age in mouse brains and that this correlates with increased expression of the SORBS3 gene (encoding vinexin) in older mouse and human brain tissue.
Regulation Gene YAP/TAZ
Year 2022
Pubmed ID 34848853
Title Vinexin contributes to autophagic decline in brain ageing across species
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA