A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Ets-1
Type gene
Species Homo sapiens
Tissue skin
Experiment Method Western blot,radioimmunoprecipitation,other
Up/Down Up
Pro/Anti Pro
Funtion Description Accumulation of senescent cells contributes to the reduced regenerative capacity in aged tissues. Analysis of the expression and activity of p16(INK4a) regulators showed that stem cell depletion, reduced proliferation, and p16(INK4a) upregulation in kerat
Regulation Gene NA
Year 2010
Pubmed ID 19907431
Title Bmi-3 reduction plays a key role in physiological and premature aging of primary human keratinocytes.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA