A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-486
Type gene
Species Mice
Tissue NA
Experiment Method quantitative reverse transcription-polymerase chain reaction ,luciferase reporter assay,Western blotting
Up/Down NA
Pro/Anti NA
Funtion Description Age-related loss of miR-486 expression was improved, skeletal muscle atrophy and apoptosis were downregulated, and mitochondrial activity and autophagy were upregulated in the adult-MICT group.
Regulation Gene PTEN
Year 2021
Pubmed ID 34398060
Title Lifelong Exercise in Age Rats Improves Skeletal Muscle Function and MicroRNA Profile
Drug NA
Disease NA
Environment Factors Lifelong exercise
Circulating NA
Variant NA
High-throughput NA