Details
| Name | hsa-mir135a-5p |
| Type | gene |
| Species | Homo sapiens |
| Tissue | skin |
| Experiment Method | RT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We showed that keratinocytes respond to the calcium induced block of cell division by a large increase of the expression of several miRNAs (hsa-mir542-5p, hsa-mir125a, hsa-mir135a-5p, hsa-mir196a-5p, hsa-mir491-5p and hsa-mir552-5p). The pitfall of this rescue mechanism is a dramatic change in gene expression which causes a further impairment of the epidermal barrier. |
| Regulation Gene | NA |
| Year | 2021 |
| Pubmed ID | 34339392 |
| Title | The life in a gradient: calcium, the lncRNA SPRR2C and mir542/mir196a meet in the epidermis to regulate the aging process |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |