A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name EXO1
Type gene
Species Homo sapiens
Tissue blood
Experiment Method PCR,other
Up/Down Down
Pro/Anti Pro
Funtion Description This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative spl
Regulation Gene NA
Year 2018
Pubmed ID 29449545
Title Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA