| Name |
FBXO31
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
Real-time reverse transcription-PCR.Western blot,Coimmunoprecipitation and affinity purification
|
| Up/Down |
Down
|
| Pro/Anti |
pro
|
| Funtion Description |
We have shown that FBXO31, although located just distal to this BAC, can induce cellular senescence in the breast cancer cell line MCF-7 and is the likely candidate senescence gene. FBXO31 has properties consistent with a tumor suppressor, because ectopic
|
| Regulation Gene |
NA
|
| Year |
2005
|
| Pubmed ID |
16357137
|
| Title |
FBXO31 Is the Chromosome 16q24.3 Senescence Gene, a Candidate Breast Tumor Suppressor, and a Component of an SCF Complex
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|