| Name |
Nox4
|
| Type |
gene
|
| Species |
Mice
|
| Tissue |
lung
|
| Experiment Method |
western blots and real-time PCR,ChIP assays
|
| Up/Down |
Down
|
| Pro/Anti |
Anti
|
| Funtion Description |
Overall, our study demonstrates that histone H4K16Ac regulates a group of pro-fibrotic genes in age-related lung fibrosis, and the potential importance of developing personalized epigenetic modifiers as targeted therapies.
|
| Regulation Gene |
NA
|
| Year |
2022
|
| Pubmed ID |
34976199
|
| Title |
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice
|
| Drug |
NA
|
| Disease |
lung fibrosis
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|