A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name GABRA2
Type gene
Species Mice
Tissue NA
Experiment Method Quantitative qRT-PCR
Up/Down Up
Pro/Anti NA
Funtion Description Overall, H3K9me3 repression at BDNF and GABA receptor promoters decreased with age. Our findings suggest that exercise and SUV39H1 inhibition differentially modulate BDNF and GABRA2 expression in an age dependent manner.
Regulation Gene NA
Year 2021
Pubmed ID 34970138
Title Exercise Reduces H3K9me3 and Regulates Brain Derived Neurotrophic Factor and GABRA2 in an Age Dependent Manner
Drug SUV39H1
Disease NA
Environment Factors exercise
Circulating NA
Variant NA
High-throughput NA